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Babyfaced Assassin
New member
I posted a while back about Creatine Serum and its effectiveness and someone else asked about it too and after researching i've found this article whcih can help ppl so i decided to share it with everyone here 
The latest data on Serum Creatine:
http://www.npicenter.com/index.asp?action=NBViewDoc&DocumentID=4262
A study presented at the 2003 Experimental Biology Meeting
today in San Diego, California comparing the effect of
creatine monohydrate powder to "creatine serum" marketed by
Muscle Marketing USA, in side-by-side, placebo controlled
tests show that while creatine monohydrate supplementation
as offered by Degussa under the Creapure? brand increases
creatine levels in muscles by about 30 percent, the Muscle
Marketing USA creatine serum product is totally ineffective,
equivalent in performance to the placebos.
Consumers should not be misled by the claim stated on
MMUSA's creatine serum labels that it contains creatine
equivalent to 2.5 g of creatine monohydrate. Accepted
analyses by many reputed scientists show that MMUSA's
product does not contain any significant amounts of creatine
but a degradation product, creatinine, instead [1]. Another
earlier study showed that creatine serum had no effect on
plasma creatine levels [2].
Muscle biopsies on subjects taking creatine serum according
to the instructions on the MMUSA label (1 serving a day for
5 days) showed no effect on muscle creatine. Even a higher
dose of creatine serum intake (8 servings a day purportedly
providing 20 grams/day of creatine monohydrate equivalent
for 5 days - supplementing more than one complete bottle (1
1/3 bottles)) resulted in no significant effect on muscle
creatine or ATP levels.
This study was designed and supervised by a leading and
widely-respected authority in the field, Prof. Richard B.
Kreider, of the Exercise & Sport Nutrition Lab at Baylor
University, in collaboration with Dr. Darryn Willoughby at
Texas Christian University and Dr. Mark Tarnopolsky at
McMaster University in Ontario, Canada [3].
According to Dr. Kreider. "The best way to determine the
potential efficacy of a creatine product is to measure the
effect the supplement has on increasing muscle creatine
stores. Creatine monohydrate supplementation resulted in a
significant increase in muscle Creatine. In contrast, this
study clearly indicates that low and high dose ATP
Advantage Creatine Serum has no effect on muscle creatine
or ATP levels, hence Creatine Serum is ineffective in
enhancing performance."
Any claims that creatine serum produces the desired effects
of creatine monohydrate are unfounded. No peer-review
articles show that creatine serum in fact increases creatine
levels in the blood or muscle. The scientific literature
shows the opposite to be true [2,3].
As the market leader for powdered creatine under the
Creapure brand, Degussa BioActives will not accept any
scientifically false claims about creatine powder.
[1] A.K. Dash, A. Sawhney. A simple LC method with UV
detection for the analysis of creatine and creatinine and
its application to several creatine formulations. J Pharm
Biomed Anal 2002, 29, 939-945. [2] A. Almada, R. C. Harris,
D. B. Harris. Ingestion of creatine serum has no effect on
plasma creatine. FASEB J 15:LB61, 2001. [3] R Kreider , D
Willoughby, M Greenwood, E Payne, G Parise, M Tarnopolsky.
Creatine Serum supplementation has no effect on muscle ATP
or creatine levels. Federation of American Societies of
Experimental Biology Annual Meeting. April 15, 2003. San
Diego, CA.
The latest data on Serum Creatine:
http://www.npicenter.com/index.asp?action=NBViewDoc&DocumentID=4262
A study presented at the 2003 Experimental Biology Meeting
today in San Diego, California comparing the effect of
creatine monohydrate powder to "creatine serum" marketed by
Muscle Marketing USA, in side-by-side, placebo controlled
tests show that while creatine monohydrate supplementation
as offered by Degussa under the Creapure? brand increases
creatine levels in muscles by about 30 percent, the Muscle
Marketing USA creatine serum product is totally ineffective,
equivalent in performance to the placebos.
Consumers should not be misled by the claim stated on
MMUSA's creatine serum labels that it contains creatine
equivalent to 2.5 g of creatine monohydrate. Accepted
analyses by many reputed scientists show that MMUSA's
product does not contain any significant amounts of creatine
but a degradation product, creatinine, instead [1]. Another
earlier study showed that creatine serum had no effect on
plasma creatine levels [2].
Muscle biopsies on subjects taking creatine serum according
to the instructions on the MMUSA label (1 serving a day for
5 days) showed no effect on muscle creatine. Even a higher
dose of creatine serum intake (8 servings a day purportedly
providing 20 grams/day of creatine monohydrate equivalent
for 5 days - supplementing more than one complete bottle (1
1/3 bottles)) resulted in no significant effect on muscle
creatine or ATP levels.
This study was designed and supervised by a leading and
widely-respected authority in the field, Prof. Richard B.
Kreider, of the Exercise & Sport Nutrition Lab at Baylor
University, in collaboration with Dr. Darryn Willoughby at
Texas Christian University and Dr. Mark Tarnopolsky at
McMaster University in Ontario, Canada [3].
According to Dr. Kreider. "The best way to determine the
potential efficacy of a creatine product is to measure the
effect the supplement has on increasing muscle creatine
stores. Creatine monohydrate supplementation resulted in a
significant increase in muscle Creatine. In contrast, this
study clearly indicates that low and high dose ATP
Advantage Creatine Serum has no effect on muscle creatine
or ATP levels, hence Creatine Serum is ineffective in
enhancing performance."
Any claims that creatine serum produces the desired effects
of creatine monohydrate are unfounded. No peer-review
articles show that creatine serum in fact increases creatine
levels in the blood or muscle. The scientific literature
shows the opposite to be true [2,3].
As the market leader for powdered creatine under the
Creapure brand, Degussa BioActives will not accept any
scientifically false claims about creatine powder.
[1] A.K. Dash, A. Sawhney. A simple LC method with UV
detection for the analysis of creatine and creatinine and
its application to several creatine formulations. J Pharm
Biomed Anal 2002, 29, 939-945. [2] A. Almada, R. C. Harris,
D. B. Harris. Ingestion of creatine serum has no effect on
plasma creatine. FASEB J 15:LB61, 2001. [3] R Kreider , D
Willoughby, M Greenwood, E Payne, G Parise, M Tarnopolsky.
Creatine Serum supplementation has no effect on muscle ATP
or creatine levels. Federation of American Societies of
Experimental Biology Annual Meeting. April 15, 2003. San
Diego, CA.
