Winstrol for improving androgen sensitivity...

[muscleup]

Huck great post !!! I think you have to be the most intelligent fucker on this entire board. Everytime you post something I have to go back and read it slowly about 2-3 times just to get it all...again thanks you're a great asset to this board.

 

[the*_Rat]

Great mother fuckin post, Brah! The best drug to lower that nasty SHBG, besides Winstrol, is Andriol. It's about the only thing that this drug is good for. Peace

 

[B182]

Any of you folks who have researched proviron as an anabolic aid have undoubtedly at one time or another heard the theory of it tying up Sex-Hormone-Binding-Globulin,which is,for lack of better word,a pain in the ass hormone that renders a good amount of the testosterone and androgen molecules you inject inactive...Thus by tying up this hormone or eliminating it's binding capacities to the androgens in your system,you free much more of them up to reach their targeted receptors and invoke anabolic responses...Well,FORGET ABOUT PROVIRON FOR THIS PURPOSE!!Check this study out which shows winstrol's ability to combat SHBG and improve androgen receptor sensitivity-This means it very well could help you get much more effectivity out of your other anabolics(primarily testosterone)and increase your overall anabolism of the OTHER steroids your using in a stack with it!Not to mention,it's about 3 million times more anabolic than proviron...Enjoy my brotha's.

J Clin Endocrinol Metab 1989 Jun;68(6):1195-200


Sex hormone-binding globulin response to the anabolic steroid stanozolol: evidence for its suitability as a biological androgen sensitivity test.

Sinnecker G, Kohler S.

Department of Pediatrics, University of Hamburg, West Germany.

Both the androgen-induced decline in serum sex hormone-binding globulin (SHBG) levels during puberty and the anabolic effect of exogenous testosterone are absent in patients with androgen insensitivity (testicular feminization). To determine whether the androgen-induced decline in serum SHBG could be used as a test of androgen sensitivity, we studied the effect of the anabolic-androgenic steroid stanozolol (17 beta-hydroxy-17 alpha-methyl-5 alpha-androstano-[3,2-c]pyrazol) on serum SHBG in 25 control subjects, 3 patients with complete androgen insensitivity, and 4 patients with partial androgen insensitivity. Stanozolol was administered orally for 3 days (0.2 mg/kg.day); blood samples were taken before and 5, 6, 7, and 8 days after the beginning of the test for measurements of serum SHBG. The lowest value (i.e. the peak response) in each subject was used as the measure of the response to stanozolol. In the control subjects the mean nadir serum SHBG level was 51.6 +/- 5.9% (+/- SD) of the initial value (P less than 0.001). In the 4 patients with partial androgen insensitivity the nadir serum SHBG ranged from 73-89%, and in the 3 patients with complete androgen insensitivity it ranged from 93-97% of the initial value. Thus, the decrease in serum SHBG after short term administration of stanozolol reflects androgen responsiveness and, thus, may be used to differentiate patients with androgen insensitivity syndromes from those with other causes of male pseudohermaphroditism.

Nice post, thanks. One thing though- SHBG is NOT a hormone.

 

[Fukkenshredded]

Yup. Winny is king for potentiating test. This was discussed on AF last year, I seem to recall...good research, Huck. As usual, you have brought a very valid, but often overlooked, point of view to the discussion of anabolics. There is some more research on winny done in about 1996 that will convert almost any skeptic. My fascination with winny is pretty well known on these boards. You are bringing lots of the reasons to light, huck! Next, you'll start producing actual studies that show trenbelone to actually assist in fat burning...

 

[The Iron Game]

Very good and interesting post with some interesting reason not to use winstrol at the end of a cycle on its own. Although making people depressed would be a result of what exactly?

Thanks Big guy

 

[athlete03]

Huck, I say this with upmost honesty: your threads kick ass. Thank you, thank you, thank you...

 

[JUICEMAN]

Huck, Excellent Post. Just one quick question though. So, since the effects of the testosterone are going to be increased when using the winstrol, does that mean that you are more likely to develope side effects such as gyno. Would it be smart to lower your test doseage when using winny?

 

[HUCKLEBERRY FINNaplex]

There will be more free'd up testosterone molecules,so yes that opens the possibilty of more estrogenic conversion.BUT-that's what we have arimidex/liquidex for.Winny and arimidex + Testosterone = the largest amount of test you will ever have reach it's targeted receptors to invoke anabolism.

 

[ORANGE_JUICER]

huck is 25mg a day enough to combat shbg?????????

 

[HUCKLEBERRY FINNaplex]

Yep,that would be benificial.