I have seen mixed reports. At low doses it is not suppressive, there are studies that support this, but the doses were 1-3mg ED. At higher doses I have seen people report suppressive activity and slight lipid changes.
I have some and I am going to run 10mg ED for 8 weeks. I am getting blood work done before and after (and maybe during). I get my blood work done next week and I will post everything here, including my blood work.
The problem with most of these substances is people (1) don't get blood work done or (2) get it done while on. I saw a post here were someone was using it and got blood work done while on. That is not going to tell you if it is suppressive (but it will show whether it affects other organs like the liver).