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Noopept...experiences from a long term user

John Juan

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***Click on the SuperiorPeptide banner in my signature for (Noopept) in the Research Liquids section***

POSTED FROM LONGECITY.ORG

Noopept is my favourite nootropic, and I've tried a lot of them! But I've noticed especially after using noopept daily for several months (a little less than half a year), a lot more good effects than simply the cognitive enhancing effect I sought after when first starting.

First I want to shortly discuss the cognitive effects I've noticed. Noopept for me seems to work on several different levels. It enhances my perception quite remarkably. Vision is most noticeable. It's like I not only notice details more, but the overall picture becomes clearer. This is hard to explain, but it's a clear effect when visiting crowded centres where a lot of peripheral motion is present. My mind seem to be able to keep track of the relative motions of all the people in my periphery, as well as the details I'm focusing on at the moment. When starting dosing I found myself thoroughly examining the patterns in the side-walk and walls. Here the detail is more pronounced.

Other senses are affected as well. My olfactory sense seems to be able to distinguish certain scents to a larger degree, it's almost like the resolution has been turned up. Hearing was one of the things that clearly was affected when starting, but it is not as noticeable after long term dosing for me. At the start though, it was bizarre.

I tried some high dose experiments (40-50mg) the first few days and I seriously thought I had gotten some strange psychedelic RC instead! When listening to music there were a clear 'distortion' and my mind felt almost a little bit tripping. But no hallucinations were present, strange indeed. After a while I came to the conclusion that what really was happening was I had acquired a more selective ability to focus. The apparent distortions of music were in fact the result of my attention rapidly shifting to the environment to my thoughts and back to the music and causing a noticeable difference in the experienced music (does this make sense to someone else?).

After a few days (and lowering of the dose) the strange psychedelic effects did lessen sharply and I were more confident that it was actually noopept (mushroom smell). A friend after trying for a few days were really surprised that it worked (he's always been sceptical to my claimed effects of racetams and other nootropics)! He did say that the experience was like the "cognitive improvements from LSD without the hallucinations".

When it comes to memory I really notice a strong effect. It's not like I have a constant feeling of my present memory capabilities, but memories I thought were long lost suddenly appears in a vivid fashion. Also, it's much easier to keep track of how I got to a certain place in my mind, my spatial memory is clearly affected. I haven't measured direct learning though, but I have all reasons to expect it is improved.

After some week something totally unexpected happened. It suddenly were A LOT easier to deal with people! To understand the revolution here you must understand that I've always had great problems with understanding other peoples irrational rules (social customs) and behaviours, and therefore I've had a hard time accepting them. Also, I've a really hard time memorizing faces as well as understanding speech, they don't come as naturally to me as for other people. This leads to not an insecurity with people (not in the sense of ordinary social anxiety/phobia) but an unwillingness to be in crowded areas and confrontations because I simply don't understand behaviours or rules I'm supposed to align to (it's like a mystery). This has all changed DRAMATICALLY. With long term dosage, I more and more feel like "I get" humans so to say. I no longer have the constant sense that I'm caught in a herd of faceless animals when visiting crowded places and I can hear what people are saying over phone.

Another surprising effect is on my feelings. I wouldn't really call noopept directly euphoric, but definitely indirectly. I can suddenly find myself crying of joy on the bus because of the wonders of the existence of the mind and the universe. It's like I see the world more of the machine that it is, and the gears really are wonderful. Also people - they too are quite euphoric (someone said MDMA-like affections which is understandable).

Another effect is the pleasure derived from music. Before I of course enjoyed music, but now it's on a different plane. Music (especially orchestral) can at times feel like a really good massage for the eardrums (hard to explain the feeling, but it's pleasurable). Also I feel like I hear all the instrument at the same time to a greater degree.

I've read of some peoples experience with a lowering of the libido, and to some degree I agree but not entirely. For me I can maybe find myself overall less sexual, but when aroused there's no difference (no impotence so to say). Also there's a very clear shift in how much time I spend looking at pretty women when outside for example. It's like I more understand and appreciate the beauty and sexuality of the attractive gender.

When it comes to dosing daily over a long time, I find that taking a break on weekends (that is 2/7 days a week) seems sufficient. Tolerance builds up for sure, but I'm not really of the opinion that this is a result of a lesser sensitivity to the drug as to a more accustomed mind. I do mostly take these breaks because the effect on Monday is profound (with the crying and all) and to limit a possible tolerance (although I think it would be perfectly usable daily without breaks).

There's one clear side effect though, and that is the irritability. I as many others, have noticed an irritability especially directed at other people. This I do not have great problems with, and it's definitely worth to trade off for everything else. I'm suspected it has something to do with an increased perception (real or not) of intelligence, and therefore an irritation directed at those less fortunate (at the beginning I could have some serious rants at stupidity - not any more). Another reason I suspect is that as the focus are deepened, the irritation spawns from the distractions (which often are people). I'm glad to say however that with daily dosage it's a lot easier to handle.

Over long time I find an increasing effect though (as opposed to pure tolerance). Sure, I don't notice the direct effects as much but it really lingers and builds up which is noticeable when I compare my mindset now to that of the time before starting this experiment. I completely believe that noopept is causing some lasting changes in the brain. I'm suspecting this has to do with some build-up of neurotrophic factors (NGF/BDNF) but I don't have some scientific basis for that claim. It would though both explain the build-up and lasting effects I notice, as well as the initial euphoria (often reported from cerebrolysin users). I sure as hell wouldn't say that it looses it's effect after time, but yes, it's clearly less noticeable. That makes sense to me though, since we mostly thrive on difference and not a static state or slow build-up.

A summary of all of this would be a general feeling of a greater existence. It's like me and my mind are more 'there' in the environment and the world as a whole. I live, feel and experience more so to say. If being drunk is a low level of existence (I actually feel like it is), this is the exact opposite.

Oh, the doses I've been taking is mostly (95%) one time daily (at morning) of ~30mg.

So, thought about this? Is someone else having profound long term effects and thinking that they have finally found THE nootropic for them?
 
Noopept is the most favorite nootropic for many researchers. Started on this recently...
 
Is this article supposed to make people want to try this stuff? Because it definitely did the opposite for me and I have absolutely no interest after reading it. Also, one paragraph says how it makes it so much easier to understand and deal with others, yet another explains a side effect is how it causes irritability towards people so I'm really lost to it's benefits, just sounds like a synthetic opiate if you ask me.
 
Noopept Effects: Introduction to the Short-Term & Long-Term Effects


Noopept is one of the most exciting and powerful Nootropics to hit the market in a long time. As a derivative member of the Racetam family, the supplement has a very low level of toxicity is very well-tolerated by almost everyone. It poses very significant benefits for multiple dimensions of cognition including enhanced learning, reasoning and memory. Since it is much more potent than most of the other Racetam supplements, you will only need to take a very small dose in order for it to be effective, making it very affordable as well. Many users and potential users wonder exactly how Noopept works, whether there are any side effects, and what the potential short-term and long-term benefits might be. The following article will take you through some of the most common Noopept effects and mechanisms of action.

How Noopept Works:
Most people who are thinking about buying Noopept start their investigation by focusing the effects of this supplement without understanding exactly how it work. While the exact mechanism of action is still not entirely understood, it does appear to function similarly to Piracetam (the original Nootropic) in many ways. Once ingested orally, the supplement is absorbed through the GI tract and then eventually crosses the blood-brain barrier. It reaches maximum concentrations within the brain in about 15 minutes, so it is also pretty fast acting.


Even when compared to Piracetam, this supplement has a very high oral bioavailability rate. Some studies indicate this may be as high as 90 percent. This means that almost all of the Noopept taken will end up in circulation, reaching the brain and optimizing your cognitive processes.

Once in the brain, Noopept reacts strongly with the Glutamatergic AMPA receptor sites. It binds to these receptors site and then helps to prevent the break down of the neurotransmitter Glutamate. While other basic Nootropics such as Piracetam only have weak effects on Glutamate, this supplement appears to exert a much stronger influence. As it binds to these sites, Glutamate is allowed to move between brain cells more easily, helping to increase a number of cognitive benefits including enhanced brain plasticity. Glutamate is the most prevalent neurotransmitter in the brain and when you increase the efficiency with which it works you can dramatically improve the communications and computations that occur between neurons.

Possible Noopept Side Effects:
There are very few, if any, observed negative side effects related to Noopept. In fact, the evidence indicates that it might help to prevent headaches, which is a side effect commonly associated with many of the Nootropics. This is possibly due to the fact that Noopept influences Glutamate more directly.

Since a very small dose is typically required to show effects, Noopept does not ordinarily show any kind of gastrointestinal distress or other stomach issues. There is, however, a small chance of developing an allergic reaction. Additionally, a small number of users have reported some irritability when using this supplement for an extended period of time.

If high doses are used, there are some other potential side effects. In such cases, it is possible that much less of the supplement will be able to be absorbed into the bloodstream and this could lead to nausea and stomach upset. Other reported high dose side effects are insomnia and elevated blood pressure.

Short-Term Noopept Effects:
There are also some significant short-term benefits associated with Noopept. A number of studies have shown it to be effective at improving memory, learning capacity, and recall. The intensity of these effects will vary from person to person, with some people being able to recall dreams vividly and others simply feeling much more productive with increased energy and motivation. Noopept also may help to increase focus, concentration, and attention span. This can further enhance the effects of increased memory and learning capacity, especially for students who are studying for long periods of time. Noopept is also great for verbal fluency and linguistic processing, an important effect for anyone in social settings who wants to be able to think on their feet more quickly.



Long-Term Noopept Effects:
There are also a number of potentially long-term effects associated with Noopept. In the area of memory, this supplement is thought to have a strong positive effect on the later stages of the memory process including memory consolidation and retrieval. Both of these are thought to be more critical in the area of long-term memory development as opposed to short-term working memory.

This supplement is also very neuroprotective in nature. Not only does it act as an anti-oxidant, helping to rid the brain of calcium and other toxins, but it can serve to help defend against other poisons like apoptosis in the neurons. It may even be able to reverse damage done due to excessive alcohol consumption. Some people use Noopept supplements for anti-aging benefits and to potentially reduce the effects of cognitive decline with age.

Noopept has also been shown to increase levels of Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). The NGF is believed to be responsible for influencing the growth and survival of certain types of neurons, while BDNF also encourages specialization of new neurons and synapses. It is these developments, particularly the new synapses which are thought to be very important in long-term memory, overall intelligence, and cognitive health. It may also help to form new connections and improve the overall level of communication between both hemispheres of the brain. The positive effects of Noopept most certainly outweigh the negatives and you will find this an excellent addition to any brain supplement regimen.
 
I notice my memory is quite poor in the evening after a full day. Upon waking is the only time it's semi decent these days. Will look further into this supplement.
 
Noopept stacks very well with other nootropics... modafinil and alpha gpc...
 
I find piracetam to be both much cheaper and much more effective than noopept. Oxiracetam was effective for me also. I found oxiracetam to be more stimulating than piracetam, but not as good for focus or creativity. Pramiracetam was excellent for logical insight and mathematics. I didn't get much noticeable effect from aniracetam except for highly color saturated vision. I have also tried nefiracetam and thought it to be weaker than piracetam. At some point I may try phenylpiracetam.

The racetams do seem to work better when combined with a source of choline. I was taking CDP choline, but substituted it for the much cheaper choline citrate. I don't notice any difference when comparing the addition of CDP choline to choline citrate.
 
Noopept stacks very well with other nootropics... modafinil and alpha gpc...


I've have ok experiences with modafinil. It does a good job enhancing clarity. It does tend to make me irritable as a side effect though. Armodafinil works much better for me. It gives me even more clarity and a lot of energy.
 
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