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lowering SHBG/ otc &/or prescription
- Thread starter triguy
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hhajdo
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From a T-Mag article: Testosterone Unleashed!
by Dr. Lonnie Lowery
• Under-eating is related to higher SHBG concentrations.
• Over-training is related too.
• Over-eating, conversely, lowers SHBG.
• Insulin is inversely related to SHBG levels.
• Particular supplements appear to reduce SHBG binding.
In a nutshell, consuming two to three protein-carb meals before lunch and two protein-fat meals after lunch seems a decent "androgen emancipation" strategy. It should keep insulin levels reasonably high while providing both proper substrates to muscle and reducing SHBG. The probable free-Testosterone elevation over time should help the higher circulating insulin that you're cultivating do it's anabolic/ anti-catabolic thing. And let's not forget, early or late, workouts generally enable an additional carb meal post-exercise, so take advantage of them. Getting an insulin spike when Testosterone and GH are also high is like hiring three construction workers at once!
Okay, now that we know how to carefully jack-up insulin regularly enough to keep SHBG from hog tying our precious T, let's briefly talk supplements. Perhaps the most interesting is Avena sativa, or green oat, like that found in Biotest's Tribex-500. Data on this stuff are sparse but there is some suggestion that it combats SHBG. An often touted but unpublished report from the Institute for Advanced Study of Human Sexuality in San Francisco suggests that green-oat extracts do release Testosterone from its binding proteins.
And as a side note, Japanese research suggests increased luteinizing hormone (LH) secretion as well, via interactions with the anterior pituitary gland itself (6, 9). Yeah, these latter studies were done in amenorrheic women, but I told you the data were sparse! Anyhow, the combined effect could well be higher circulating concentrations of free T, even in men.
The other general approach is to simultaneously raise total T and free-T via prohormones. Although unpublished, I've seen first hand that androstenediol, for example, can raise serum Testosterone levels with the bound (SHBG-tied) and unbound levels rising simultaneously. One could very well speculate that a prohormone (or other steroid), combined with green oat supplementation and natural (or unnatural) insulin elevation could be quite the ticket for muscle anabolism.
To summarize our "unleashing" plan, we need to 1) Eat every 2-3 hours, focusing on protein with carbs in the morning and protein with "healthier fats" in the evening 2) Allow for adequate rest — perhaps two "off" days weekly — to prevent over-training 3) Limit high-volume training cycles to just a few weeks, and 4) Possibly consider a 2-4 week course of Avena sativa along with the frequent eating to see if one's prohormones, (etc.) are more effective.
With the person-to-person variation in SHBG being on the order of 40-50% (27), these "unleashing" suggestions may be just the ticket for those of you who have high SHBG and don't even know it. Although the "free hormone hypothesis" debate rages on, it is an interesting scenario — especially if we can control it. If you get less progress from a cycle of androgens than your gloating training buddy, SHBG may be involved. Perhaps the data mentioned here is your missing factor. In any case, the research suggests a new mechanism for the wonders of massive, disciplined eating.
Now go track down some of that leftover beef carcass in the fridge, will ya?
by Dr. Lonnie Lowery
• Under-eating is related to higher SHBG concentrations.
• Over-training is related too.
• Over-eating, conversely, lowers SHBG.
• Insulin is inversely related to SHBG levels.
• Particular supplements appear to reduce SHBG binding.
In a nutshell, consuming two to three protein-carb meals before lunch and two protein-fat meals after lunch seems a decent "androgen emancipation" strategy. It should keep insulin levels reasonably high while providing both proper substrates to muscle and reducing SHBG. The probable free-Testosterone elevation over time should help the higher circulating insulin that you're cultivating do it's anabolic/ anti-catabolic thing. And let's not forget, early or late, workouts generally enable an additional carb meal post-exercise, so take advantage of them. Getting an insulin spike when Testosterone and GH are also high is like hiring three construction workers at once!
Okay, now that we know how to carefully jack-up insulin regularly enough to keep SHBG from hog tying our precious T, let's briefly talk supplements. Perhaps the most interesting is Avena sativa, or green oat, like that found in Biotest's Tribex-500. Data on this stuff are sparse but there is some suggestion that it combats SHBG. An often touted but unpublished report from the Institute for Advanced Study of Human Sexuality in San Francisco suggests that green-oat extracts do release Testosterone from its binding proteins.
And as a side note, Japanese research suggests increased luteinizing hormone (LH) secretion as well, via interactions with the anterior pituitary gland itself (6, 9). Yeah, these latter studies were done in amenorrheic women, but I told you the data were sparse! Anyhow, the combined effect could well be higher circulating concentrations of free T, even in men.
The other general approach is to simultaneously raise total T and free-T via prohormones. Although unpublished, I've seen first hand that androstenediol, for example, can raise serum Testosterone levels with the bound (SHBG-tied) and unbound levels rising simultaneously. One could very well speculate that a prohormone (or other steroid), combined with green oat supplementation and natural (or unnatural) insulin elevation could be quite the ticket for muscle anabolism.
To summarize our "unleashing" plan, we need to 1) Eat every 2-3 hours, focusing on protein with carbs in the morning and protein with "healthier fats" in the evening 2) Allow for adequate rest — perhaps two "off" days weekly — to prevent over-training 3) Limit high-volume training cycles to just a few weeks, and 4) Possibly consider a 2-4 week course of Avena sativa along with the frequent eating to see if one's prohormones, (etc.) are more effective.
With the person-to-person variation in SHBG being on the order of 40-50% (27), these "unleashing" suggestions may be just the ticket for those of you who have high SHBG and don't even know it. Although the "free hormone hypothesis" debate rages on, it is an interesting scenario — especially if we can control it. If you get less progress from a cycle of androgens than your gloating training buddy, SHBG may be involved. Perhaps the data mentioned here is your missing factor. In any case, the research suggests a new mechanism for the wonders of massive, disciplined eating.
Now go track down some of that leftover beef carcass in the fridge, will ya?
What a bunch of trite horseshit. Eat more, get enough rest and take their supplements. Groundbreaking.
As for the timing recommendations -- it's all speculation designed to sound scientific.
Yep, Proviron is best -- which makes it kick Clomid's ass, but some people refuse to catch on.
As for herbs, true Avena Sativa has been shown to suppress SHBG. (But you can buy it elsewhere at half the price) So has Muira Puama and Stinging Nettles. (Urtica Dioica)
It's worth a shot.
As for the timing recommendations -- it's all speculation designed to sound scientific.
Yep, Proviron is best -- which makes it kick Clomid's ass, but some people refuse to catch on.
As for herbs, true Avena Sativa has been shown to suppress SHBG. (But you can buy it elsewhere at half the price) So has Muira Puama and Stinging Nettles. (Urtica Dioica)
It's worth a shot.
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