Interesting discussion on muscltalk by "TheDoctor" about using nolvadex to treat gyno

[Lift Chief]

Buy Nolvadex to treat Gyno

He is a doctor who helps out with certain issues over on the UK board muscletalk. I found this very interesting- hope you guys do as well- and i hope this has not already been covered 1,000 times:



I am familiar with study 4,and use this as the Tamoxifen/gyno gold standard study in terms of reasonable number of patients and study design.


1
Clomiphene in the treatment of adolescent gynecomastia. Clinical and endocrine studies.
Plourde PV, Kulin HE, Santner SJ.

Conclusion:
Clomiphene citrate 50 mg/day-results not significant


2
Effects of Tamoxifen on lipid profile and coagulation parameters in male patients with pubertal gynecomastia.
Novoa FJ, Boronat M, Carrillo A, Tapia M, Diaz-Cremades J, Chirino R.

Conclusion: Some good effects on lipids

3
Treatment of gynecomastia with Tamoxifen: a double-blind crossover study.
Parker LN, Gray DR, Lai MK, Levin ER.

.
Excellent study design,shame they didnt have more subjects.
Conclusion:
70% showed significant improvement of gyno(but none got rid of it)
10% developed gyno symptoms after Tamoxifen stopped
Need to repeat study and run Tamoxifen for longer than a month.


4
Comparison of Tamoxifen with danazol in the management of idiopathic gynecomastia.
Ting AC, Chow LW, Leung YF.

Another excellent(and my favourite study on this topic)
78% "cured" with Tamoxifen
40% "cured" with danazol
However higher recurrence rate(22%)of gyno after Tamoxifen stopped.


5
Tamoxifen for flutamide/finasteride-induced gynecomastia.
Staiman VR, Lowe FC.

CONCLUSIONS:
Good results but talks about gyno symptoms(pain)as opposed to gyno
mass


6
An endocrinological study of persistent pubertal macromastia.
Aritaki S, Miyazawa H, Ogihara M, Ushio M, Izumizawa A.


Interesting study.
No significant results.




7
[Treatment of marked gynecomastia in puberty with Tamoxifen]
[Article in German]
Konig R, Schonberger W, Neumann P, Benes P, Grimm W.


10 boys were treated with the Tamoxifen (Nolvadex) at a dose of 20-40 mg/d orally for 2-12 months.
In most cases the gynecomastia decreased totally, only two patients experienced palpable subareolar glandular tissue at the end

Conclusion:
Bit vague in how many got rid of gyno.
20% still had/or gyno came back after treatment



8
Danazol therapy in gynaecomastia; recent experience and indications for therapy.
Buckle R.

Not ideal for BBers,inhibits pituitary hormones.


9
[Testosterone and estradiol levels in male gynecomastia. Clinical and endocrine findings during treatment with Tamoxifen]]

14/16(88%)gyno partially or fully regressed.
2(12%)no effect on gyno
No recurrence.


SUMMARY
From the above studies:
For established gyno
20mg Tamoxifen]
2 to 3 months

Average
75% chance of regression or complete resolution
20% chance it will come back again.

In addition I would presume you would only get these results when you are not on AS and could reoccur again on next cycle.

--he also said he has not seen any studies to indicate that topical DHT works to reduce gyno. Doesn't mean it won't work just that he hasnt seen it.

 

[Lift Chief]

I guess no one cares- oh well i'll bump it then let it die

 

[mvmaxx]

I've found that Nolvadex definitely helps. Good post bro.

 

[icelandic]

nolva will reduce localized water retention and swelling in a similar manner to andractim and yohimburn, but it cannot reduce the glandular mass which is most responsible for the pointy nipples.

 

[shifti]

Bump good post bro! I always knew that long term treatment with nolvadex would decrease gyno. It makes sense if you think about it. I will be doing this next year for 6 months while off cycle.

 

[Lift Chief]

nolva will reduce localized water retention and swelling in a similar manner to andractim and yohimburn, but it cannot reduce the glandular mass which is most responsible for the pointy nipples.

That's true- nothing can really be done if it's a hard mass under the nipple. But i know a lot of us here have just localized swelling and fat deposits under the nipple. And if that's the case this may help

 

[mvmaxx]

nolva will reduce localized water retention and swelling in a similar manner to andractim and yohimburn, but it cannot reduce the glandular mass which is most responsible for the pointy nipples.

Not true. I've personally experienced a reduction in glandular tissue while on Nolvadex. I'm not talking about water retention or fat either.

 

[icelandic]

Really, How long were you on until you noticed a reduction?

 

[mvmaxx]

Really, How long were you on until you noticed a reduction?

I was in the 3rd week of a sust/dbol/decca cycle when I noticed my preexisting gyno from childhood had gotten bigger. It went from being absolutley unnoticeable to slightly noticeable. Note, I had no itchiness, pain etc. That came about a week later. I quit the dbol and got some Nolvadex. The pain stopped after about 2-3 days with the Nolvadex and then after about 2 weeks @ 40mg/ED it had reduced to it's original size. I continued with the sust/dbol and never had any more problems. I now include Nolvadex in every cycle.

 

[icelandic]

OK so nolva simply reduced your steroid induced gyno back down to its pre-steroid size?