Yes, I get the tingling which leads to numbness, not fun. I got it at both 4 and 8IU dialy, gonna start up again soon at 2IU and see what happens.
I have yet to find a difinitive answer but ive heard it causes swelling of the soft tissue around the nerves and thus preasure and numbness. The sides do often go away after a while if you stay on but I personally havent found a dose I can stay on to overcome the sides at.