For the best fat burning resultz I would go with an IV injection right before bed. The GH peaks more rapidly and you save close to 40% that you would normally loose through a sub-q injection before the GH enters the blood stream. It also increases vascularity more more so through IV injections. As for a localized fat burner I have never heard that theory about Growth Hormones, but rather water injections for localized fat loss. The idea is that by injecting water in the fat it sends signals to the cell to release the stored water which in turn reduces the size of the cell because a fat cell is something like 95% water. I have tried this method with no positive results but some people swear by it. Marc 371, if you find a study that state that GH causes localized fat loss or is a localized fat burner I would love to see it.