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genezapharmateuticals
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puritysourcelabs
Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

Europe and the United States the ICU sepsis and septic shock prognosis

candywhy

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Severe sepsis and sepsis septic shock caused by a high mortality rate, and the differences in the different studies ranged from 22% -76%, which are important factors. Treatment and hospitalization in the ICU (intensive care unit) is one of the important part. Professor Mitchell Levy MD, United States Brown University of Respiratory and Critical Care Medicine, use of RNF111 rescue sepsis action data in hospitals in Europe and the United States, conducted a cohort study to compare the comparison of their overall prognosis. The study found that Europe sent to ICU patients with more severe disease, compared with the United States of its higher crude mortality, ICU patients transferred from the RNF114 hospital to more. The study was published in the the Lancet Infectious Dieases November 2012.The study uses the data of SSC (save sepsis action), more than 200 centers in the United States and Europe. Only the patient's admission time from January 2005 to January 2010, at least 20 bed hospital and ICU patients hospitalized for more than three months before inclusion in the analysis. Each hospital only the first four years of the RNF122 enrolled patients included in the cohort analysis. The diagnosis of severe sepsis and septic shock patients are transferred from the emergency room or ward to intensive care units (ICUs), these patient data are input to the database of the SSC. 25,375 patients were included in this cohort study. 18,766 patients (74%) of the 107 centers in the United States, Europe included 6609 patients (26%) of the 79 hospitals. ICU admission from the emergency department, while in Europe, 3405 patients (51.5%) 12,218 (65.1%) patients in the United States, revenue from the ward.

The research results show that the time to stay in the RNF123 ward before income ICU, compared to Europe much longer. (1.0vs0.1 days gap 0.9,95% confidence interval 0.8-0.9). The crude mortality rate in Europe than the United States (41.1% vs 28.3%, the gap between 12.8, 95% CI, 11.5 -14 • 7). ICU average length of stay (7.8 vs 4.2, 3.6, 3.3 -3 • 7) and overall length of stay (22.8 vs 10.5 Tian, 12.3, 11.9 -12 • 8), in Europe than the United States high. Adjusted RNF125 mortality rate in Europe is no longer significantly higher than that of the United States. (32.3% vs 31.3%, 1.0, -1 • 7 to 3.7, p = 0.468). Patients conducted in full accordance with all appropriate fluid resuscitation of sepsis guidelines, the United States than in Europe, high (21.6% vs18 • 4%, 3.2, 2.2 -4 • 4).Discussed in unadjusted mortality, Europe and the United States have a significant difference. But after sepsis seriousness adjusted data show differences disappear. Europe and the United States compared to heavier patients admitted into the ICU from the ward more patients (patients sent to the United States from the emergency more). The study on the ICU the efficiency of the medical model, and how to effectively use the resources raised new problems.

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