Posted by PA on March 15, 1997 at 18:08:39:
In Reply to: Re:yea, but....... posted by Animal on March 15, 1997 at 17:37:04:
: : : : Someone posted a message a few days ago (it's lost now) asking for DNP synthesis information. As self-proclaimed local archivist/researcher, I happened to have an article on it in my files:
: : :
: : : : DDuchaine wrote:
: : : : How to make DNP:
: : : : 50g Benzene
: : : : 5gm mercuric nitrate
: : : : 300g nitric acid (50%)
: : : : Stir, heat to 50C for 5 hr.
: : : : 500ml cold water, chill
: : : : filter DNP out, wash with water and dry.
: : : : Now:
: : : : add:
: : : : 500ml water
: : : : 20gm lye
: : : : filtrate
: : : : HCl until acidic
: : : : Chill, filter, water wash & dried.
: : : : PS: Most of you will blow yourselves up doing this.
: : : :
: : : : Dan Duchaine
: : : : E-mail inquiries may not be responded because of time
: : : : restraints or annoying/boring questions.
: : : : Phone consultations and contest prep available.
: : : : E-mail my manager for rates and times at:
: : : : [email protected]
: : :
: : : : -APF
: : : If you can do this and get all this stuff you would have by now figured out how to
: : : get DNP. This will cost you more than buying the DNP, let alone you will probably kill
: : : yourself trying to synthesize it. Futhermore, I don't see how it can WORK! Maybe I'm missing something
: : : here and PA or somebody can let me know if I'm wrong, but where does the phenol come in. After the boiling
: : : you have dinitrobenzene. This is not DNP. He is telling us that you can now throw in some lye and that is
: : : going onto a deactivated dinitrobenzene ring? What reaction is this? Maybe I'm wrong but I don't think
: : : it works that way. Anarchy in the USA!
: : I don't know the mechanism but there is a reaction called oxynitration where an aromatic
: : compound reacts with mercuric nitrate and concentrated nitric acid and the product
: : contains both hydroxy and nitro groups. In the case of benzene the products are 2,4 DNP or
: : 2,4,6-TNP (picric acid, KABOOM!!)depending on the reaction conditions.
: : PA
: Right, but how are you going to control which position the nitro goes onto? ortho-para, or all. OH is one of the highest activating groups you can put on
: a benzene and no matter what you are going to get some TNP. I wouldn't even try this one! Anarchy in the USA!
I wrote this synthesis for Duchaine and it was much more detailed than what is presented here. The oxynitration
reaction will always give you a mixture of di and tri nitrated phenols. However there is a wide enough difference
in solubility in water between the di and tri that the di can probably be pretty selectively crystallized out
in water. Even if there is a few percent of tri (picric acid) nitrated impurity left I don't think it
will be a terribly dangerous thing (compared to taking DNP itself) anyway.
- R:thanks PA....... Animal 10:35:04 3/18/97