Can you convert IU's into ml's?

Posted: 07-Jan-2002 09:17 AM

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Excerpt: Lets say you have 18iu, can you convert this into ml? Just wondering because the concept of IU has always confused me. SAF...

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Can you convert IU's into ml's?

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Can you convert IU's into ml's?

Old 07-Jan-2002, 09:17 AM   #1
SAF
United States
Lets say you have 18iu, can you convert this into ml? Just wondering because the concept of IU has always confused me.

SAF
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Old 07-Jan-2002, 09:38 AM   #2

IU'S are means of measuring concentration that is why you you will see for example 16iu's per ml etc.

You will need to see what context the 18iu's are in. By that I mean if you have a vial with gh - growth hormone (somatropin) - in that is 36iu's per ml then it stans to reason that 18iu's would mean that you have .5ml of the soultion.

However there is no direct correlation or conversion between IU's and ml's
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Old 07-Jan-2002, 10:39 AM   #3

Purple is right. It sounds like your doing serostim, so the ML = the amount of sterile water you use to mix it. If you are trying to use a specific # of IU's just devide it. IE 1/2 cc = 9IU's 1/4 = 4 1/2 IU's.
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Old 07-Jan-2002, 10:57 AM   #4

1mg of substance equals 3IU. So serostim 6mg is 18IU. Suppose I want to do 3IU for 6 days. So now add 6 ml of sterile water to the 18IU vial. Your concentration is now 18IU per 6ml or 3IU per ml. Now, you inject 1ml (which contains 3IU). This is why you guys had to learn algebra.
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Old 07-Jan-2002, 11:23 AM   #5

"1mg of substance equals 3IU. "

An IU has NO milligram, microgram, gram, etc. equality. An IU is an International Unit, which is a measurement of ACTIVITY, not true weight/mass. An IU is determined by an international commitee of scientists who wish to standardize biological compounds, such as vitamins (A, E, D, etc.), hormones (insulin, gh - growth hormone (somatropin) - , etc.).

So in the case of gh - growth hormone (somatropin) - , 1mg DOES equal 3IU's, but this is not the case for any other compound, such as beta-carotene, which is something like 6.25mg equals 1,000 IU's.

Also, IU's cannot be equated to a volume, since this is arbitrary. The IU's/ml is determined by the person who makes the solution.
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Old 07-Jan-2002, 11:41 AM   #6

Originally posted by DrJMW
1mg of substance equals 3IU. So serostim 6mg is 18IU. Suppose I want to do 3IU for 6 days. So now add 6 ml of sterile water to the 18IU vial. Your concentration is now 18IU per 6ml or 3IU per ml. Now, you inject 1ml (which contains 3IU). This is why you guys had to learn algebra.


Hey Doc, since you're the one that sta in school the longest

What if I put the 6ml in the vial but want to use a insulin pin to inject. How many IU per insulin pin unit would I be talking about?
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Old 07-Jan-2002, 12:14 PM   #7

hey drjmw, i was one of those kids in school who would ask the teacher when i would ever need to know algebra. if i only knew then what i know now. . . hee hee.

one thing to note. . . 1 IU will equal different MG's depending on how you mix in the case of gh - growth hormone (somatropin) - . you can make it so 1IU will equal 1mg or 3mg or whatever you choose.
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Old 07-Jan-2002, 01:04 PM   #8

Originally posted by dezl
"1mg of substance equals 3IU. "

An IU has NO milligram, microgram, gram, etc. equality. An IU is an International Unit, which is a measurement of ACTIVITY, not true weight/mass. An IU is determined by an international commitee of scientists who wish to standardize biological compounds, such as vitamins (A, E, D, etc.), hormones (insulin, gh - growth hormone (somatropin) - , etc.).

So in the case of gh - growth hormone (somatropin) - , 1mg DOES equal 3IU's, but this is not the case for any other compound, such as beta-carotene, which is something like 6.25mg equals 1,000 IU's.

Also, IU's cannot be equated to a volume, since this is arbitrary. The IU's/ml is determined by the person who makes the solution.
dezl is correct here... I think the confusion is coming in because some here are using Serostim as the example. In the case of Serorstim, if it is reconstituted with the provided vial of water, your solution will be 18IU, in the slightly more than 1ml solution.
In the case of Serostim, the 1ml of reconstituted gh - growth hormone (somatropin) - equals 100IU's on the standard insulin needle. So if you divide the 18IU (total volume of the reconstituted gh - growth hormone (somatropin) - in one vial) by 100 (as determined on an insulin needle), it would take 5.5IU (on an insulin needle) to equate to 1IU of reconstituted gh - growth hormone (somatropin) - . Hopefully this makes sense???
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Old 07-Jan-2002, 01:10 PM   #9

When I stated that 1mg=3IU, I was on topic for human growth hormone - somatropin - . Now if you take 18IU and dilute it with 10ml (cc), then you will get 1.8IU per ml (cc). So, for a 'insulin syringe/needle (28g, 1/2", 1cc), you would get 1.8IU.
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Old 07-Jan-2002, 02:55 PM   #10
United States
boys and girls out there of all ages, DO NOT use this method or any type of method when using insulin......that is all.
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