What is the half life of HCG?

Posted: 27-May-2003 04:10 PM

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Excerpt: What is the half life of HCG? I did some searching but have not come up with an answer. I would think the half life would have to be know to determine an appropriate dose schedule....

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What is the half life of HCG?

 

 

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What is the half life of HCG?

Old 27-May-2003, 04:10 PM   #1
United States
What is the half life of HCG - human chorionic gonadotropin - ? I did some searching but have not come up with an answer. I would think the half life would have to be know to determine an appropriate dose schedule.
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Old 27-May-2003, 04:42 PM   #2

How come I never thought of that? Good point!
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Does 33 hours for hCG halflife seem right?

Old 27-May-2003, 06:33 PM   #3
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I did some more searching and came up with this:

The HCG - human chorionic gonadotropin - elimination halflife-time EHT is about 33 hours for intramuscular or subcutaneous injections.

Does 33 hours for HCG - human chorionic gonadotropin - halflife seem right?
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Old 27-May-2003, 09:24 PM   #4

One point that you may consider is that the effects may long exceed the half-life.

According to the PDR
Pregnyl (HCG - human chorionic gonadotropin - )

It approves the following regimens depending on Physician's prefernce:
For cyrptochridism in pre-pubertal males not due to anatomcial obstruction
1- 4000 USP 3 x a week for 3 weeks
2- 5000 USP every 2nd day for 4 injections
3-15 injections of 500-1000 USP over 6 weeks
4- 500 USP 3x weekly for 4-6 weeks
For selected cases of of hypogonadotropic function
1- 500-1000 USP 3x a week for 3 weeks, followed by same dose 2 x a week for 3 weeks
2- 4000 USP 3 x a week for 6-9 months then reduced 2000 USP 3 x a week for 3 more months




Now I am guessing that steroid inhibition is not what the above indictated uses are for. It seems to me to try a selected dose for 3 x a week for a week or 2, and if that doesnt do it, do more. This does not seem to be an exact science here. Every other med in the PDR is pretty specific. I am also guessing 1 USP = 1 IU. But I will find out for sure on that.

Pharmguy
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