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Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

compund 14 ?

Anyone else heard of compound 14?

Here is an article on it.
Scientists have synthesized a new compound that ‘mimics’ exercise. Could a workout pill be far behind? - The Washington Post

"gave compound 14 to two different groups of mice. One group was fed a normal diet and the other a high-fat diet which made them obese and impaired their glucose tolerance, an early sign of pre-diabetes.
The results were intriguing: In the normal diet group, blood glucose and weight remained normal. But in the high-fat diet group, a single dose of compound 14 lowered blood glucose to near normal levels. A daily dose for seven days caused them to lose 5 percent of their body weight."

"Dubbed "compound 14," the new molecule does this by triggering a chain reaction of events in the cell. Compound 14 inhibits the function of an enzyme called ATIC which plays a central role in insulin signaling in the body. That in turn leads to the build up of something called ZMP -- known as a "master regulator" of metabolism -- in the cells. It's ZMP that makes cells think they have run out of energy and activate the cell's central energy censor which is known as AMPK"
 
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